DrugRepV_3530 | Carbinoxamine maleate | Respiratory System | Allergic rhinitis, vasomotor rhinitis and allergic conjunctivitis | Influenza virus | A/Puerto Rico/8/1934(H1N1) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3531 | Carbinoxamine maleate | Respiratory System | Allergic rhinitis, vasomotor rhinitis and allergic conjunctivitis | Influenza virus | A/Guizhou/54/1989(H3N2) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3532 | Carbinoxamine maleate | Respiratory System | Allergic rhinitis, vasomotor rhinitis and allergic conjunctivitis | Influenza virus | A/Shanghai/37T/2009(H1N1) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3533 | Carbinoxamine maleate | Respiratory System | Allergic rhinitis, vasomotor rhinitis and allergic conjunctivitis | Influenza virus | B/Shanghai/2017(BY) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3534 | Carbinoxamine maleate | Respiratory System | Allergic rhinitis, vasomotor rhinitis and allergic conjunctivitis | Influenza virus | A/H7N9/4664T/2013 (H7N9) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3535 | Chlorpheniramine Maleate | Respiratory System | Allergic reactions | Hay fever | Rhinitis | Urticaria | Asthma | Influenza virus | A/Puerto Rico/8/1934(H1N1) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3536 | Chlorpheniramine Maleate | Respiratory System | Allergic reactions | Hay fever | Rhinitis | Urticaria | Asthma | Influenza virus | A/Guizhou/54/1989(H3N2) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3537 | Chlorpheniramine Maleate | Respiratory System | Allergic reactions | Hay fever | Rhinitis | Urticaria | Asthma | Influenza virus | A/Shanghai/37T/2009(H1N1) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3538 | Chlorpheniramine Maleate | Respiratory System | Allergic reactions | Hay fever | Rhinitis | Urticaria | Asthma | Influenza virus | B/Shanghai/2017(BY) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_3539 | Chlorpheniramine Maleate | Respiratory System | Allergic reactions | Hay fever | Rhinitis | Urticaria | Asthma | Influenza virus | A/H7N9/4664T/2013 (H7N9) | | CPE reduction assay | Decrease (50 %) | Approved | 30459739 |
DrugRepV_4103 | 2-(4-tert-butylphenyl)-N-[(E)-(3,4-diethoxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4104 | 2-(4-tert-butylphenyl)-N-[(E)-(3,5-dibromo-4-methoxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4105 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4106 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(trifluoromethyl)phenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4107 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(methylsulfanyl)phenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4108 | 2-(4-tert-butylphenyl)-N-[(E)-(4-methylphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4109 | 2-(4-tert-butylphenyl)-N-[(1E)-2-[(1-methylnaphthalen-2-yl)oxy]ethylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4110 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(propan-2-yl)phenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4111 | 2-(4-tert-butylphenyl)-N-[(1E)-1-phenylpropylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4112 | N-[(E)-(4-bromophenyl)methylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4113 | N-[(E)-(4-hydroxyphenyl)methylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4114 | N-[(E)-(4-cyclohexylphenyl)methylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4115 | N-[(1E)-1-(4-methoxyphenyl)ethylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4116 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(3,4-diethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4149 | 2-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4150 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(trifluoromethyl)phenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4151 | N-[(E)-(4-hydroxyphenyl)methylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4152 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4153 | N-[(1E)-1-(4-methoxyphenyl)ethylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4154 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(3,4-diethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4155 | 2-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4156 | 2-(4-tert-butylphenyl)-N-[(E)-(4-hydroxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4157 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4158 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-methylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4159 | (2E)-3-(4-methylphenyl)-N-[(E)-(4-methylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4160 | (2E)-N-[(E)-(4-methylphenyl)methylidene]-3-phenylprop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4161 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-[4-(propan-2-yl)phenyl]methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4162 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-tert-butylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4163 | (2E)-3-(4-tert-butylphenyl)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4164 | (2E)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-3-phenylprop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4165 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-phenylmethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4166 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-nitrophenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4167 | (2E)-3-(4-tert-butylphenyl)-N-[(1E)-1-(4-chlorophenyl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4168 | (2E)-3-(4-tert-butylphenyl)-N-[(1E)-1-(pyrazin-2-yl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4169 | (2E)-3-(4-tert-butylphenyl)-N-[(1E)-1-(4-ethoxyphenyl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4170 | (2E)-N-[(1E)-1-{[1,1-biphenyl]-4-yl}ethylidene]-3-(4-tert-butylphenyl)prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4171 | (2E)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-(4-methylphenyl)prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4172 | (2E)-3-(4-tert-butylphenyl)-N-{[4-(trifluoromethyl)phenyl]methyl}prop-2-enamide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4173 | (2E)-3-phenyl-N-{[4-(trifluoromethyl)phenyl]methyl}prop-2-enamide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4174 | (2E)-N-({[1,1-biphenyl]-4-yl}methyl)-3-(4-tert-butylphenyl)prop-2-enamide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4175 | (2E)-N-({[1,1-biphenyl]-4-yl}methyl)-3-phenylprop-2-enamide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4176 | 3-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]propanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4177 | N-[(E)-(4-ethoxyphenyl)methylidene]-3-phenylpropanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4178 | 3-(4-tert-butylphenyl)-N-[(E)-(4-methylphenyl)methylidene]propanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4179 | N-[(E)-(4-methylphenyl)methylidene]-3-phenylpropanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4180 | 3-(4-tert-butylphenyl)-N-[(E)-(4-hydroxyphenyl)methylidene]propanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4181 | N-[(E)-(4-methylphenyl)methylidene]-3-phenylpropanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4182 | 3-(4-tert-butylphenyl)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]propanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4183 | N-[(E)-(4-cyclohexylphenyl)methylidene]-3-phenylpropanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4224 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4225 | 3-[(E)-{[2-(4-methylphenyl)-1H-indol-3-yl]methylidene}amino]-1-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4226 | (2E)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-[4-(propan-2-yl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4227 | (2E)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-[4-(trifluoromethyl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4228 | (2E)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-(4-methoxyphenyl)prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4229 | (2E)-3-{[1,1-biphenyl]-4-yl}-N-[(E)-(4-ethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4230 | (2E)-N-[(E)-(4-methylphenyl)methylidene]-3-[4-(propan-2-yl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4231 | (2E)-N-[(E)-(4-methylphenyl)methylidene]-3-[4-(trifluoromethyl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4232 | (2E)-3-(4-methoxyphenyl)-N-[(E)-(4-methylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4233 | (2E)-3-{[1,1-biphenyl]-4-yl}-N-[(E)-(4-methylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4234 | (2E)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-3-[4-(propan-2-yl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4235 | (2E)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-3-[4-(trifluoromethyl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4236 | (2E)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-3-(4-methoxyphenyl)prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4237 | (2E)-3-{[1,1-biphenyl]-4-yl}-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4238 | (2E)-N-[(E)-(4-hydroxyphenyl)methylidene]-3-[4-(propan-2-yl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4239 | N-[(E)-(4-ethoxyphenyl)methylidene]naphthalene-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4240 | N-[(E)-(4-ethoxyphenyl)methylidene]quinoline-3-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4241 | N-[(E)-(4-ethoxyphenyl)methylidene]quinoline-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4242 | N-[(E)-(4-ethoxyphenyl)methylidene]-1H-indole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4243 | N-[(E)-(4-ethoxyphenyl)methylidene]-1H-1,3-benzodiazole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4244 | N-[(E)-(4-methylphenyl)methylidene]naphthalene-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4245 | N-[(E)-(4-methylphenyl)methylidene]quinoline-3-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4246 | N-[(E)-(4-methylphenyl)methylidene]quinoline-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4247 | N-[(E)-(4-methylphenyl)methylidene]-1H-indole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4248 | N-[(E)-(4-methylphenyl)methylidene]-1H-1,3-benzodiazole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4249 | N-[(E)-(4-hydroxyphenyl)methylidene]naphthalene-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4250 | N-[(E)-(4-hydroxyphenyl)methylidene]quinoline-3-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4251 | N-[(E)-(4-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4252 | N-[(E)-(4-hydroxyphenyl)methylidene]-1H-indole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4253 | N-[(E)-(4-hydroxyphenyl)methylidene]-1H-1,3-benzodiazole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4254 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]naphthalene-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4255 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]quinoline-3-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4256 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]quinoline-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4257 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-1H-indole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4258 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-1H-1,3-benzodiazole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4259 | 3-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-oxopropanehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4260 | 3-(4-tert-butylphenyl)-N-[(E)-(4-methylphenyl)methylidene]-3-oxopropanehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4261 | 3-(4-tert-butylphenyl)-N-[(E)-(4-hydroxyphenyl)methylidene]-3-oxopropanehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4262 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(E)-[(4-ethoxyphenyl)methylidene]amino]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4263 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(E)-[(4-methylphenyl)methylidene]amino]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4264 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(E)-[(4-hydroxyphenyl)methylidene]amino]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4265 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(E)-[1-(4-cyclohexylphenyl)ethylidene]amino]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4266 | 1-[(E)-[(4-ethoxyphenyl)methylidene]amino]-3-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4267 | 1-[(E)-[(4-methylphenyl)methylidene]amino]-3-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4268 | 1-[(E)-[(4-hydroxyphenyl)methylidene]amino]-3-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4269 | 1-[(E)-[1-(4-cyclohexylphenyl)ethylidene]amino]-3-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4270 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(4-ethoxyphenyl)methyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4271 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(4-methylphenyl)methyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4272 | 1-benzyl-3-[(1E)-2-(4-tert-butylphenyl)ethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4273 | 1-[(4-methoxyphenyl)methyl]-3-[(1E)-2-phenylethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4274 | 1-[(4-methylphenyl)methyl]-3-[(1E)-2-phenylethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4275 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-(4-methylphenyl)urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4276 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-(4-hydroxyphenyl)urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4277 | 1-(4-methylphenyl)-3-[(1E)-2-phenylethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4278 | 1-(4-hydroxyphenyl)-3-[(1E)-2-phenylethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4279 | N-[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]-4-ethoxybenzohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4280 | N-[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]-4-methylbenzohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4281 | 2-[(1E)-2-(4-tert-butylphenyl)ethenyl]-5-(4-ethoxyphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4282 | 2-[(1E)-2-(4-tert-butylphenyl)ethenyl]-5-(4-methylphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4283 | 2-[2-(4-tert-butylphenyl)ethyl]-5-(4-ethoxyphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4284 | 2-[2-(4-tert-butylphenyl)ethyl]-5-(4-methylphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4285 | 2-(4-ethoxyphenyl)-5-(2-phenylethyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4286 | 2-(4-methylphenyl)-5-(2-phenylethyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4287 | 4-{5-[2-(4-tert-butylphenyl)ethyl]-1,3,4-oxadiazol-2-yl}phenol | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4288 | 2-[(4-tert-butylphenyl)methyl]-5-(4-ethoxyphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4289 | 2-[(4-tert-butylphenyl)methyl]-5-(4-methylphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4290 | 4-(4-methylphenyl)-1-(2-phenylethyl)-1H-1,2,3-triazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4291 | (2E)-3-(4-tert-butylphenyl)-N-(5-methyl-1H-1,3-benzodiazol-2-yl)prop-2-enamide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4292 | (2E)-N-(1H-1,3-benzodiazol-2-yl)-3-(4-tert-butylphenyl)prop-2-enamide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4293 | 3-(4-tert-butylphenyl)-N-(5-methyl-1H-1,3-benzodiazol-2-yl)propanamide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4294 | N-(1H-1,3-benzodiazol-2-yl)-3-(4-tert-butylphenyl)propanamide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4295 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | Approved | 29499487 |
DrugRepV_6169 | 4-{1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-5-yl}-2-methoxyphenol | NA | NA | Dengue virus | NA | | CPE reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6176 | 4-{[1,1-biphenyl]-4-yl}-2-[(2E)-2-(phenylmethylidene)hydrazin-1-yl]-1,3-thiazole | NA | NA | Dengue virus | NA | | CPE reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_7976 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S2.1 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7977 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S2.2 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7978 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S2.3 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7979 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S3 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7980 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S4.1 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7981 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S4.3 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7982 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S5 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7983 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S7 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7984 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S8 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7985 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S9 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |